Khoom Taw Qhia
Shikimic acid hmoov yog cov organic compound nrog cov mis molecular ntawm C7H10O5. Nws yog xim tsis muaj xim lossis dawb koob zoo li muaju. Solubility nyob rau hauv dej ntawm 20 ° C yog 18%, me ntsis soluble nyob rau hauv ethanol thiab ether, thiab yuav luag insoluble nyob rau hauv chloroform thiab benzene. Los ntawm kev cuam tshuam cov metabolism ntawm arachidonic acid, shikimic acid inhibits platelet aggregation, inhibits tsim ntawm arterial thiab venous thrombosis thiab cerebral thrombosis, thiab muaj anti-inflammatory thiab analgesic teebmeem. Nws kuj tseem siv tau los ua cov tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob nruab nrab. Cov khoom no feem ntau yog siv los ua cov tshuaj nruab nrab, uas yog khaus thiab yuav tsum tsis txhob siv ncaj qha.
Yam khoom
Khoom npe: hnub qub anise extract
Lub npe Latin: Illicium verum Hook.f.
Ib feem siv: txiv hmab txiv ntoo qhuav
Specification: 10: 1
Cov tsos mob: 10% -98% shikimic acid
Tamiflu' cov khoom tseem ceeb shikimic acid. Lub shikimic acid tam sim no siv los ntawm Roche yog ua tiav thiab muab rho tawm los ntawm lub hnub qub anise.
Cov txheej txheem ntawm synthesizing shikimic acid los ntawm petrochemical raw cov ntaub ntawv yog nyuaj, thiab tsis muaj ntau lawm thiab daim ntawv thov nqi tsuas yog rau kev tshawb fawb.
Pharmacological teebmeem Shikimic acid hmoov muaj cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob los ntawm kev cuam tshuam cov metabolism ntawm arachidonic acid, inhibiting platelet aggregation, thiab inhibiting tsim ntawm arterial thiab venous thrombosis thiab cerebral thrombosis. Nws kuj muaj anti-inflammatory thiab analgesic nyhuv. Nws kuj tuaj yeem siv los ua tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob nruab nrab, nrog rau kev tiv thaiv Cov teebmeem ntawm cov tshuaj tiv thaiv kab mob khaub thuas noog" Tamiflu" thiab" Keflu". Shikimic acid pathway Txoj kev shikimic acid yog ib txoj hauv kev tseem ceeb hauv metabolic uas muaj nyob rau hauv cov nroj tsuag, fungi thiab kab mob.
Shikimic acid hmoov yog siv los ua cov khoom pib ntawm oseltamivir (cov khoom xyaw nquag ntawm Tamiflu), uas yog cov tshuaj tiv thaiv neuraminidase thiab tuaj yeem siv los kho thiab tiv thaiv kab mob khaub thuas A thiab mob khaub thuas B.
Cov yam ntxwv ntawm lub cev | ||
Particle Loj | 100% Los ntawm 80 mesh | Ua raws |
Poob rau ziab | ≤5% | |
tshauv | ≤5% | |
Cov hlau hnyav | ||
Methanol | ≤ 3000mg / kg | Ua raws |
acetone | ≤ 5000mg / kg | Ua raws |
n-hexane | ≤ 290mg / kg | Ua raws |
Qhov ntom | ||
xoob ntom | ≥ 0.30g / ml | Ua raws |
ceev ceev | ≥ 0.50g / mL | Ua raws |
Kev ntsuam xyuas microbiological | ||
Tag nrho cov phaj suav | ≤3000cfu / g | Ua raws |
Tag nrho cov poov xab& Pwm | ≤300cfu / g | Ua raws |
E.Coli | Tsis zoo | Tsis zoo |
Salmonella | Tsis zoo | Tsis zoo |
Staphylococcus | Tsis zoo | Tsis zoo |
Cia: Khaws rau hauv qhov zoo kaw, lub teeb-resistant, thiab tiv thaiv los ntawm ya raws. |
Toxicity
mob toxicity, plab kab noj hniav-nas LD50: 600 mg/kg
Lub warehouse yog qhov kub thiab txias, ventilated thiab qhuav.
Cim npe nrov: Shikimic Acid hmoov, Tuam Tshoj, tuam ntxhab, lwm tus muag khoom, Hoobkas, yuav, pheej yig, tsis tshua muaj nqi, organic, ntshiab ntuj, zoo, GMP tau ntawv pov thawj, ISO tau ntawv pov thawj, 100% ntuj, Hoobkas mov, kub muag
